Pew Pew Slime Idle RPG starts off cute and simple, but the moment your slime evolves into its first mutation, the entire game turns into a build-crafting experience.
Each mutation branches into a full progression path, and how strong your slime becomes depends not just on raw stats, but on how you pair skills and pals with your chosen mutation type.
Since rerolling and experimenting can take time, this guide breaks down everything you need to know, from how mutations differ, to which builds scale the best, to what pals and skills complement each path.
If you’re starting your first evolution or planning your long-term min-max build, this guide covers every major decision.
How Mutation Paths Work
Your slime evolves through branches tied to three core playstyles:
- Projectile / Basic Attack Mutations
Focus on attack speed, crits, bullets, and direct DPS. - Skill-Based Mutations
Damage comes from abilities rather than basic attacks. - Pal-Focused Mutations
You act as a support unit while pals deal most of the damage.
Each mutation line evolves into an ultimate form that deepens the branch and adds unique passives.
The best builds align mutation perks with matching skills and pals, mixing archetypes leads to slower scaling and wasted damage potential.
Tier List Overview (Standalone Performance Ranking)
This tier list ranks mutations based on how strong they are without rare rolls, heavy investment, or perfect pals, meaning their raw identity and reliability.
| Tier | Mutation Focus | Notes |
|---|---|---|
| S-Tier | Frost Seraph | Reliable damage, crowd-control, scales with elements |
| A-Tier | Earth Spirit, Abyssal Tidelord, Nocturnis Dragonlord | Strong, but depend on gear, crit scaling, or timing |
| B-Tier | Behemoth Guardian, Punk Squad | Can scale hard but rely too much on pal AI and positioning |
Now let’s break each mutation down.
S-Tier Mutations
Frost Seraph (Projectile / Attribute Damage)
Best For: sustained DPS, attribute scaling, safe long-term damage
Strength Style: basic attacks + frost DoT + freezing + multi-bullet combos
Frost Seraph evolves from projectile mimicry and focuses on attribute damage rather than raw numbers.
Basic attacks inflict frost damage, while passives trigger extra frost bombs and freezing effects every few attacks.
This gives it a mix of:
- Safe, consistent damage
- Crowd control
- DoT through frost domain effects
Why it’s strong:
It doesn’t require defensive skills or specific high-rarity pals to be effective. Attribute scaling gives value even in bad rolls.
Weakness:
Lacks self-defensive buffs, so survival depends on CC rather than tank stats.
Best Build Direction:
Stack attribute damage effects, add multi-hitting projectiles, and use pals that boost elemental output.
A-Tier Mutations
Earth Spirit (Projectile / Basic Attack Damage)
Best For: simple, high flat damage
Strength Style: bullet spam + multipliers on base attack
Earth Spirit focuses on raw basic attack scaling.
Instead of slowing enemies or specializing in frost DoT, it simply increases base attack damage and starts firing extra bullets after every few attacks.
Pros:
- Very high flat damage numbers
- Easy scaling, no specific synergy needed
- Great for farming waves
Cons:
- No defensive traits
- No elemental backup when taking damage
- Falls off against enemies that punish brute-force builds
Best Build Direction:
Buff raw attack speed and crit; treat this as a “shred everything fast” build.
Abyssal Tidelord (Skill-Based Damage, Fast Cooldowns)
Best For: skill spam builds and fast burst damage
Strength Style: reduced cooldowns, tentacle summons, rapid cast rotation
Abyssal Tidelord speeds up skill recovery and hits hardest when cycling abilities quickly.
Later passives summon tentacles each time a skill is used, turning rotation frequency into both offense and defense.
Pros:
- Extremely high burst once skills cycle fast
- Chain effects from tentacles add AoE control
- Scaling improves exponentially with legendary skills
Cons:
- Relies heavily on getting good skill rolls
- Weak early if you don’t build cooldown reduction
Best Build Direction:
Maximize cooldown speed, prioritize skills that hit multiple targets, pair with pals that trigger bonus effects on casts.
Nocturnis Dragonlord (Skill-Based Crit Damage)
Best For: slow but massive bursts
Strength Style: crit damage scaling + delayed power ramp
Nocturnis Dragonlord is a skill-type mutation like Abyssal Tidelord, but instead of cooldown speed, it focuses on amplifying crit damage.
Its damage ramps over time, peaking once passives activate, then drops devastating AoE via Dragonbone-style zone effects.
Pros:
- Tremendous crit bursts
- Strong late-battle scaling
- Good for long boss fights
Cons:
- Needs time to charge damage
- Vulnerable early in battles
- Requires better survivability planning
Best Build Direction:
High crit damage, timed effects, survival skills to tank early damage.
B-Tier Mutations (High Potential, Low Control)
Behemoth Guardian (Pal-Focused Support)
Best For: team-wide buffs, boss phases
Strength Style: damage reduction, pal boosts, emergency healing
This mutation buffs pals instead of dealing damage itself. It gives damage reduction, boss bonuses, and emergency healing at low HP, plus summons additional crit-boosted pal units.
Why it ranks lower:
Pal AI can wander, break positioning, or miss enemies while you dodge, making damage inconsistent.
Best Build Direction:
Stack tanking, buff allies, use skills that trigger extra summons.
Punk Squad (Pal-Focused Crit Offense)
Best For: full pal crit builds
Strength Style: boosting pal crit rate, extra bullets, timed bonus damage
Punk Squad is more offensive than Behemoth Guardian but suffers from the same AI-dependency issues and lacks self-defensive tools.
Best Build Direction:
Big crit scaling, automated bullet spam, tanky pals.
Best Pals for Each Mutation
These suggestions match mutation strengths rather than rarity alone.
Best Pals for Frost Seraph
- Grilled Squid
- Collector Perry
- Octopus Pirate King
- Naru Turtle
- Bahamut
Focus on attribute amplification, survivability, and burst effects.
Best Pals for Earth Spirit
- Collector Perry
- Octopus Pirate King
- Dr. Malayan Tapir
- Cool Cauliflower
- Golden Sparrow
Prioritize basic attack synergy and attack speed boosts.
Best Pals for Behemoth Guardian & Punk Squad
- Capybara Detective
- Dr. Malayan Tapir
- SKY-99
- Superstar
- King Slime
Look for pals that buff crit, speed, or spawn allies.
Best Pals for Abyssal Tidelord & Nocturnis Dragonlord
- King Penguin
- Dr. Malayan Tapir
- Lady Belle
- Tamamo no Mae
- King Slime
Focus on skills triggered by casting or timed bursts.
Best Skills (By Mutation Type)
Frost Seraph
- Frost Totem
- Slime Machine Gun
- Mythical Elf
- Black Hole Devour
- Blade Domain
Prioritize multi-hits + attribute domain effects.
Earth Spirit
- Slime Machine Gun
- Mythical Elf
- Black Hole Devour
- Ancient Stone Sphere
- Blade Domain
Flat damage + bullet density > utility.
Behemoth Guardian & Punk Squad
- Airship Companions
- Mythical Elf
- Black Hole Devour
- Ancient Stone Sphere
- Dragon’s Flame
Look for summons, extra units, and passive buffs.
Abyssal Tidelord
- Thunderbolt Storm
- Mythical Elf
- Black Hole Devour
- Ancient Stone Sphere
- Satellite Strike
Cooldown synergy + multi-cast effects.
Nocturnis Dragonlord
- Thunderbolt Storm
- Mythical Elf
- Black Hole Devour
- Ancient Stone Sphere
- Satellite Strike
Crit multipliers + heavy AoE long-interval skills.
Which Mutation Should You Choose First?
- If you want the strongest early game: Frost Seraph
- If you want big raw damage: Earth Spirit
- If you want active ability gameplay: Abyssal Tidelord
- If you want huge crit explosions: Nocturnis Dragonlord
- If you want team-based chaos: Behemoth Guardian / Punk Squad
Overall, I think:
- Choose mutations based on playstyle, not just numbers.
- Skill builds scale harder late game, but need investment.
- Projectile builds are the most reliable early and mid-game.
- Pal builds are niche and fun, but less consistent.
If you’re unsure what to pick: Projectile – Frost Seraph is the safest long-term path.
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